Skip to main content


BODIPY Based phand selected metal ions sensors

Issue Abstract

Abstract
Despite the fact that development of many pH indicators with different groups is quite challenging, many works have been take place. pH factor have a drastic influence on human beings. It has wide applications like biological imaging and environmental monitoring,so it is necessary to measure pH. Many pH indicators have been developed and synthesized based on water soluble BODIPY modified with various groups such as aldehydes, nitro, hydrazine, amines,Schiff bases,hydroxyl aryl etc. Herein, we are presenting numbers pH sensors for the detection of various H+ as well as OH- in living one which can measure pH in different states and combinations such as hypochlorite detection, Hg2+ and HSO4- in aqueous media, nitric oxide and detection of pH in the real water samples. The pH sensors can also be used to measure pH in highly acidic conditions .These compounds show interesting properties such as spectral, optical, absorption and photo-physical properties and have high sensitivity and selectivity. Keywords: pH in different states and combinations such as hypochlorite detection


Author Information
Sakshi Juneja
Issue No
3
Volume No
1
Issue Publish Date
05 Mar 2022
Issue Pages
1-16

Issue References

1. W. Shi, X. Li and H. Ma, Angew. Chem., 2012, 124, 6538–6541.
2. S. G. Stratton, G. H. Taumoefolau, G. E. Purnell, M. Rasooly, W. L. Czaplyski and E. J. Harbron, Chem. – Eur. J., 2017, 23, 14064–14072.
3. G. Li, D. Zhu, L. Xue and H. Jiang, Org. Lett., 2013, 15, 5020–5023.
4. R. Wang, C. Yu, F. Yu, L. Chen and C. Yu, TrAC, Trends Anal. Chem., 2010, 29, 1004–1013.
5. M. H. Lee, N. Park, C. Yi, J. H. Han, J. H. Hong, K. P. Kim, D. H. Kang, J. L. Sessler, C. Kang and J. S. Kim, J. Am. Chem. Soc., 2014, 136, 14136–14142.
6. M. M. Salim, E. A. Owens, T. Gao, J. H. Lee, H. Hyun, H. S. Choi and M. Henary, Analyst, 2014, 139, 4862–4873.
7. (a) M. Hecht, W. Kraus and K. Rurack, Analyst, 2012, 138, 325–332; (b) D. P. Murale, K. M. Lee, K. Kim and D. G. Churchill, Chem. Commun., 2011, 47, 12512–12514.
8. M. Baruah, W. Qin, N. Basari, W. M. De Borggraeve and N. Boens, J. Org. Chem., 2005, 70, 4152–4157.

9. Y. Chen, H. Wang, L. Wan, Y. Bian and J. Jiang, J. Org. Chem., 2011, 76, 3774–3781
10. Y. Urano, D. Asanuma, Y. Hama, Y. Koyama, T. Barrett, M. Kamiya, T. Nagano, T. Watanabe, A. Hasegawa and P. L. Choyke, Nat. Med., 2009, 15, 104-109. 

11. (a)Treibs,A.;Kreuzer,F.-H.LiebigsAnn.Chem.1968. (b) Vos de Wael, E.; Pardoen, J. A.; van Koeveringe, J. A.; Lugtenburg,J.Recl.Trav.Chim.Pays-Bas1977.(c)Falk, H.;Leodolter,A. Monatsh.Chem.1978.(d)Pavlopoulos, T. G.; Shah, M.; Boyer, J. H. Appl. Opt. 1988. (e) Johnson,I.D.;Kang,H.C.;Haugland,R.P. Anal.Biochem.1991. (f) Karolin, J.; Johansson, L. B.-A °.; Strandberg, L.; Ny, T. J. Am. Chem. Soc. 1994. 

12. Baki, C. N.; Akkaya, E. U. J. Org. Chem. 2001; Karolin, J.; Johansson, L. B.-A °.; Strandberg, L.; Ny, T. J. Am. Chem. Soc. 1994. 

13. (a) Principles of Fluorescence Spectroscopy, 2nd ed.; Lakowicz, J. R., Ed.; Kluwer Academic/Plenum Publishers: New York, 199. (b) Fluorescent Chemosensors for Ion and Molecule Recognition; Desvergne, J.-P., Czarnik, A. W., Eds.; Kluwer Academic Publishers: Dordrecht, The Netherlands, 1997. (c) Handbook of Fluorescent ProbesandResearchProducts,9thed.;Haugland,R.P.,Ed.;Molecular Probes: Eugene, OR, 2002. (d) Molecular Fluorescence. Principles and Applications;Valeur,B.,Ed.;Wiley-VCH: Weinheim,Germany,2002 

14. E. Vachette, C. Fenge, J.-M. Cappia, L. Delaunay, G. Grellerand B. Magali, BioProcess Int., 2014, 12, 23–25.
15. X. Su and I. Aprahamian, Chem. Soc. Rev. 2014, 43, 1963-1981.
16. W. Guan, W. Zhou, J. Lu and C. Lu, Chem. Soc. Rev., 2015, 44,6981-7009.
17. T. W. Bell and N. M. Hext, Chem. Soc. Rev., 2004, 33, 589-598.
18. W. F. Fitzgerald, C. H. Lamborg and C. R. Hammerschmidt,Chem. Rev., 2007, 107, 641-662.
19. B. Koo and T. M. Swager, ACS Macro Lett., 2017, 6, 134-138.
20. S. Rochat and T. M. Swager, Angew. Chem. Int. Ed., 2014, 53,9792-9796. 

21. M. J. Davies, J. Clin. Biochem. Nutr., 2011, 48, 8; (b) A. J. Kettle andC. C. Winterbourn, Redox Rep., 1997, 3, 3. 22. S. Madhu, M. R. Rao, M. S. Shaikh and M. Ravikanth, Inorg.Chem., 2011, 50, 4392–4400.
23. S. Madhu, S. K. Basu, S. Jadhav and M. Ravikanth, Analyst,2013, 138, 299–306. 37. 

24. H.S. Lva, J. Liu, J. Zhao, B.X. Zhao, J.Y. Miao, Sens. Actuators B:Chem, 2013, 177, 956-963.
25. L. Chen, L. Xin, Y.L. Liu, Y. Zhao, J. Liu, P. Wang, W. Guo, Org.Biomol. Chem, 2011, 9, 2345-2349.
26. G. S. Jiao, A. Loudet, H. B. Lee, S. Kalinin, L. B. A. Johanssonb andK. Burgess, Tetrahedron, 2003, 59, 3109-3116. 27.Mariappan K., Alaparthi M., Caple G., Balasubramanian V., Hoffman MM., Hudspeth M., and Sykes AG. Selective Fluorescence Sensing of Copper(II) and Water via Competing Imine Hydrolysis and Alcohol Oxidation Pathways Sensitive to Water Content in Aqueous Acetonitrile Mixtures. InorgChem 2014;53:2953−2962

28. Y. Yang, C.-Y. Gao, N. Zhang and D. Dong, Sens. Actuators, B,2016, 222, 741. 

29.Mariappan K., Alaparthi M., Caple G., Balasubramanian V., Hoffman MM., Hudspeth M., and Sykes AG. Selective Fluorescence Sensing of Copper(II) and Water via Competing Imine Hydrolysis and Alcohol Oxidation Pathways Sensitive to Water Content in Aqueous Acetonitrile Mixtures. InorgChem 2014;53:2953−2962. 

30. Mani Vedamalai,aDhavalKedaria,b Rajesh Vasita,b Shigeki Moric and Iti Gupta*a,Daltons Transaction, 2015.