Nanocrystalline NiCexFe2-xO4 (x = 0, 0.2, 0.4 and 0.6) magnetic spinel materials were synthesized by a simple microwave combustion technique (MCT) by utilizing the fuel of Pedalium murex plant extract. The establishment of a cubic spinel structure was ensured by powder X-ray diffraction (PXRD) technique and the crystallites size was found to be in the range of 27.5 to 13.1 nm for NiFe2O4 and Ce:NiFe2O4 nanoparticles (NPs). The morphology of the NiFe2O4 NPs was observed by high resolution scanning electron microscope (HR-SEM). Energy dispersive X-ray (EDX) studies confirmed the formation of pure spinel ferrite structure as they ensured the presence of all the elements and the formation of the desired compositions. Furthermore, the band gap value was estimated to be within 3.26 and 3.39 eV. The appearance of Fourier transform infrared (FT-IR) bonds at 437 and 456 cm-1 is linked to the octahedral (B) metal stretching (Ni-O) and the band at 582 cm-1 is linked to the tetrahedral (A) metal stretching (Fe-O), which ensure the formation of cerium substituted NiFe2O4 NPs. Magnetic parameters such as remanent magnetization (Mr), coercivity (Hc) and saturation magnetization (Ms) were calculated from M-H loops, which exhibited ferromagnetic behaviour. The photocatalytic (PC) behavior of NiFe2O4, NiCe0.2Fe1.8O4, NiCe0.4Fe1.6O4 and NiCe0.6Fe1.4O4 were analyzed under visible light irradiation by the degradation (PCD) of an aqueous solution of Rhodamine B (RhB) dye.  Among the various prepared compositions, NiCe0.4Fe1.6O4 exhibits higher PCD efficiency as 93.88 % at 120 min with enhanced visible light absorption range. The antibacterial activities of gram-positive Staphylococcus aureus, Bacillus subtilis and gram-negative Escherichia coli and Klebsiella pneumonia have been investigated using pure and Ce3+ substituted NiFe2O4 NPs. It was found that the improved activity is intensified with smooth Ce3+ doping as it cause a decrease in the grain size.

The Coronavirus (COVID-19) flare-up, which started in China, has tainted countless individuals. Its spread has left organizations around the globe tallying costs. Financial specialists have been stressed over the effect of the coronavirus as it spreads outside of China. Enormous moves in financial exchanges, where participates in organizations are purchased and sold, can influence interests in certain sorts of benefits or individual investment accounts .The Financial Times Stock Exchange (FTSE), Dow Jones Industrial Average and the Nikkei have all observed sharp falls since the episode started. As per a recent report directed in New York City in 2020, analysts discovered microorganisms living on the outside of money, going from mouth and vaginal microscopic organisms to influenza like infections. The World Health Organization (WHO) prescribes washing hands in the wake of taking care of cash, particularly before eating nourishment. Furthermore, credit cards are not really any progressively clean: Microorganisms can move to visas in comparable manners and retail location terminals are utilized by numerous people. Hence moving to intangible forms of money such as cryptocurrency would be a safe exit for all individuals, business organizations and governments at this crucial time of Covid-19. The purpose of this research paper is to answer the following questions: (1) How to keep the various businesses within the cryptocurrency economy running well in the event of a coronavirus spread? (2) Why Cryptocurrency would be a Safe haven during the coronavirus crisis? (3) How Coronavirus: has shaken the worldwide economies? and (4) What is the Likely Recovery Path?

In this present work, BiFeO3 (BFO) and La0.05Bi0.95FeO3 (LBFO) nanoparticles have been synthesized using urea as a fuel via sol-gel combustion method. The synthesized materials have been analyzed by Powder X-ray diffraction (XRD), Fourier- Transform Infrared spectroscopy (FT-IR), Ultraviolet-visible (UV-Vis.) spectroscopy, High-resolution scanning electron microscopy (HR-SEM), High-resolution transmission electron microscopy (HR-TEM), Magnetic measurements and antimicrobial studies. The X-ray diffraction patterns (XRD) of BFO demonstrates the rhombohedrally distorted perovskite structure with the space group R3c. Furthermore, the average particle size of BFO and LBFO were found to be 19 and 17nm respectively. The morphological studies (HR-SEM and HR-TEM analysis) of BFO and LBFO revealed the formation of sphere shaped nanostructures with uniform grain size. Also, it was found that the grain size was decreased by doping La contents to BFO. The magnetic measurements showed a ferromagnetic behavior of LBFO and the saturation magnetization drops drastically from 7 emu/g for BiFeO3 up to 6 emu/g. The antibacterial investigation of BFO and LBFO exhibited excellent antibacterial activity against various Gram-positive and Gram-negative bacterial strains.

Quarries which are located close to surface water or ground water often face problems leading to drainage. Pseudomonas aeruginosa, can be used for biodegradation in liquid culture, but the roles and production in soils are unknown. Surface-active compounds for bacterial production like biosurfactants and bioemulsifiers which will increase the hydrocarbons of local pseudosolubility and that will improve in mass transfer to biodegrading bacteria. Potassium solubilizing bacteria, such as Acidothiobacillus ferroxidans, Bacillus mucilogenous, Pseudomonas, Burkholderia, B. edaphicus and B. circulans can be used as biofertilizer. Hence this study is focused on isolation and identification of Pseudomonas aeroginosa from quarry sand and it will be used further for more application purposes.

Janani Suraksha Yojana (JSY) stays a passive maternity interference now the National Rural Health Mission (NRHM) actuality realized by the impartial of falling motherly then neo-natal Death.  Objectives: Towards measure the efficiency of STP organized Awareness concerning between Prenatal Womenfolk. Matreials in addition Methods: A Pre investigational enquiry project. 50 pregnant women at Primary Health Centre at Namakkal District. No probability purposive sample method stood charity toward excellent the sample. STP with information questionnaires remained used to assess the knowledge. Results: The Post-test mean score for knowledge stayed adequate knowledge47 (94%) and 3(6%) had moderate knowledge. Paired’ test score for information on JSY was 7.084 showing the significant benefits of STP. Conclusion: Here remained no substantial suggestion among post-test information totals of the collection. He conducted that STP remained actual now humanizing the information Maternal Health Women.

The diagnostic method  in siddha system is based on eight fold examination“  Meikuri  niranth thoni  vizhi naa  virumalam kaikuri” The eight diagnostic methods, collectively referred to as ‘ENVAGAI THERVUGAL’ which consist of Tongue, Colour,Speech,Eyes,Stool, Urine,Touch, and Pulse All of these parameters  Urine examination-Neerkuri and Neikuri  one of the important tool and unique one in siddha system to diagnose the disease, to observe the prognosis and observe the changes according to six taste  food and three humoral derangements.  The aim of the clinical study is to validate the neikuri patterns in pandu noi –Anemia according to siddha pathology and pathogenesis of the disease.  20 diagnosed patients of anemia were selected. The urine samples were collected and the oil drop test was conducted by using the guidelines of saint theraiyar. Pitha Neer Neikuri was observed in all the 20 cases

In Indian Ayurveda various plants have been used to treat different diseases. Different types of chemical compounds have been reported in various plants. Due to which plants are medicinally important. Ageratum conyzoides is one such plants belonging to family Asteraceae Numerous chemical compounds such as flavonoids, benzofurans, sterols, coumarins, terpenoids and alkaloids have been extracted from Ageratum. Various extracts prepared from different plant parts possess pharmacological properties. In this review various ethnobotanical, pharmacological and chemical composition of this plant will be presented. Special reference is given to anti-microbial, anti-bacterial, anti-inflammatory, wound healing and anti-cancerous properties of this plant.

Protecting information is the most important process in organizations to safeguard information assets from the security risks and threats. Most organizations employ security expertise to incorporate risk assessment in early stage of website software development, or employ external personnel for security services. This study proposes a lightweight approach that improves software risk assessment in web-based applications using two applied methodologies: 1) OCTAVE Allegro risk assessment framework to identify and assess organization’s critical assets, providing robust outcomes with limited security risk assessment knowledge and expertise, 2) STRIDE threat modelling tool that identifies and measures potential threats in well-defined and timesaving ways. The outcome of this study presents secure software risk assessment by identifying organization’s critical assets, identify risks, analyse the risks and determine risks impacts. As a result, study also proposes mitigation plan and countermeasures for the assets that have critical business impacts that could be useful for organizations who are using web applications in their forthcoming information security improvement. 

Power system stability is significant to make sure energy security system a state of normal operation after being subjected to stress condition. Major events and disturbances occurring in the power system with high power demand may contribute to limited amount of power delivered to consumers, thus leading to voltage instability in the operation of the system, However, this problem can be solved based on dynamic modelling analysis. Dynamic modelling offers accurate results for voltage stability analysis as it involves real-time modelling of the system. This paper presents voltage stability index calculation to determine location of mini hydro integrated with the IEEE 14 bus system. In order to place the mini hydro connected with IEEE 14 bus system appropriately, suitable location needs to be determined on the basis of enhancing voltage stability of the power system. Fast voltage stability index (FVSI) was adopted to analyse the weakest location of bus in the system. The modelling was done based on the formulation of FVSI, integrated with control box functions in PSCAD software. Once the power flow is simulated in the PSCAD, the control box will generate the FVSI values. This modelling technique is also very useful in reducing errors due to manual calculation.

This paper presents the performance investigation of voltage and current for dynamic model of the wind turbine. In this study, the various numbers of wind turbine speed are applied in the simulation. This treatment is intended to see how much influence the turbine speed has on the voltage and current output. IEEE 14 bus system is integrated to the wind turbine in order to observe the impact of on-grid connection to the voltage and current performance.  How to model wind turbine in PSCAD simulation software also discussed in this paper. The detail of supporting components in designing a wind turbine system and their functions are also explained. Several values of turbine speed are also considered in this paper as a study material in seeing the performance of wind turbines. The relationship between wind speed and pitch angle will also be discussed to ensure that the wind turbine is not damaged. In order to prove the accuracy of the simulation model, the obtained measurement generation of active power from the wind turbine is matched with the manual calculation. Based on the various wind speed values that have been tested, this can be the basis for the application of wind turbine (renewable energy) design development for further research.

Searching for compatibility between specific sequences in long DNA sequences requires accuracy and a considerable amount of time. This research was conducted to design and implement a computational model used to search a DNA barcoding in a set of DNA sequences. To obtain optimal results, we conduct the optimization spiral dynamics algorithm. Data, i.e., a collection of DNA sequences of plants, were downloaded from the NCBI website. This study produced DNA barcode by looking at the best position index which has the best percentage of matches in each sequence. The results pointed out an increase in computational time depending on the number of sequences, the number of iterations, the number of dimensions of spiral dynamics, and the number of populations.

Remarkable increment in electricity supply has contributed to higher system stress and reactive power demand, which then results in voltage instability of power systems. One of the main reasons contributing to the voltage instability is insufficient amount of the reactive power support available in the system, due to the limitations in the output power produced by the generating units The lack of reactive power permits the failure of generator and transmission line which causes a system to collapse and leads to a higher impact on power system security and reliability. In this paper, an algorithm of Moth-Flame Optimization (MFO) was implemented to optimize the reactive power dispatch problems for voltage stability enhancement. Validation on the performance of the MFO-based reactive power dispatch optimization was performed on the IEEE 30 bus system, considering different voltage stability indices namely the Fast Voltage Stabilty Index (FVSI) and Lmn Index. It was found that the optimal setting of control variables based on the Lmn Index yields an improved performance of the test system as compared with the solutions obtained using the FVSI index.

BACKGROUND OF THE STUDY: Stroke is preventable health care problem; it is treatable condition, in most cases, if treatment is prompt and evidence based. A well-developed public education program is critical to have informed public who can recognize the sign and symptoms of a stroke and know how to respond. In addition, the health care system must be organized to provide evidenced based nursing care provided by stroke competent health care providers. Provision of highly specialized multidisciplinary care team can be elevating condition of patient. 

OBJECTIVES OF THE STUDY: The objectives of the study were to assess the existing knowledge of staff nurse regarding comprehensive nursing care plan for the stroke patients and to identify association between knowledge score and selected demographic variables.

MATERIAL AND METHOD: An evaluatory research approach with descriptive research design was used. Total 70 Subjects were selected by using purposive sampling technique. The samples were nurses who are working in critical care areas of hospital. Participants were informed about the study & written consent was taken prior to participation. The structured knowledge questionnaires were administered to assess knowledge regarding comprehensive nursing care plan for the CVA patients. The data was analyzed by using inferential and descriptive statistics.

RESULT: While assessing the existing knowledge of nurses regarding comprehensive nursing care plan for the CVA patients the majority of staff nurses shows adequate knowledge level. Out of 70 staff nurses 83% were having adequate knowledge, 17% were having moderately adequate knowledge.While assessing the association between knowledge score with selected demographic variables, and there was no significant association between knowledge score with selected demographic variable. So H1 has been failing to accept.

CONCLUSION: The aim of this study was to determine the knowledge about comprehensive nursing care plan for the CVA patients. The study concluded that, majority of participants were having adequate knowledge regarding about comprehensive nursing care plan for the CVA patients among staff nurses. Comprehensive nursing care plan is very effective for improving the patient’s condition with stroke and to minimize the complications among them. Hospital administrative staff is responsible to maintain and enhance the knowledge of staff nurses of critical care areas regarding treating protocol and updated guidelines of CVA. Therefore nurses can be adhering with standard guidelines of care plan and delivery by that patient’s outcome can be promoted.

Background: Anaemia in pregnancy is a major health problem in developing countries. More than two third of the pregnant women in India are anaemic and most of the times it is due to deficiency of iron and folic acid.

Material Methods: In this research study an evaluative research approach with pre- experimental one group pre-test-post-test design was used. The sampling technique was non probability convenience sampling is used to collect the 60 samples of antenatal mother and data collection done by administering the structured questionnaire. Data was analyzed by using descriptive and interferential statistics such as standard deviation, chi- test, and paired’ test.

Results: With regards to the pre-test assessment, the score of (41.7 %) antenatal mother having moderate level of knowledge and (58.3%) antenatal mother having inadequate knowledge while in post-test (38.3%) of antenatal mother having moderate level of knowledge and (61.7%) having adequate level of knowledge nobody was found at the inadequate level. The obtained pre-test mean score was 10.16  and after HAP it increased up to 20.68 , the mean difference of the pre-test and post-test is 10.52 The pre-test SD was 2.42 and post-test SD 3.03.The obtained “t” test value 33.68, DF=99 significant at 0.05level. It indicates that there is increased in the level of knowledge regarding management of anaemia after providing HAP. So we accept H1 and conclude that there is significant difference between pre-test and post-test knowledge score of antenatal mother. The association of protest knowledge score was only associate with the age, education, family income, No .of children others are not associate. Hence, H2 is rejected and conclude that the pre-test knowledge score is not associated with the demographic variable of the samples in this study.

Background: Zika virus is an arbovirus belongs to the genus flavivirus and pose a serious global threat. The recent 2015 outbreak in brazil was associated with a significant increase in microcepahly cases & other  neurological complications in new born babies and WHO declared ZIKA to be an international public health emergency. Currently there is no specific treatment or Vaccine available for the Zika virus and thus due to the unavailability of the antiviral drugs, the need for the identification of novel drugs are paramount.

Methodology: Qunatum –chemical parameters(DFT) and ADMET was performed to identify the drug-likeliness properties.

Results:  Among the tested Compounds, galloylquinic acid, Bacopaside III and Bacopaside A were identified as leads against multiple targets of ZIKA virus. The identified compounds also exhibited desirable quantum chemical and ADMET Properties.

Conclusion: Hence the compounds hampering the active site of the three different proteins playing prime role in replication and fusion with desirable pharmacokinetics properties could be suggested for further in vitro and in vivo analysis of ZIKA virus.

Self-medication is the selection and use of non-prescription medicines by individuals’ own initiatives to treat self-recognized illnesses or symptoms. The trend of using drugs on their own that is self-medication has been increasing in developing countries as well as in developed countries in recent years. It is practiced significantly worldwide even though its type, extent and reasons for its practice may vary. Minor ailments like sore throat, fever, cough and diarrhoea can be relieved with self-medications such as paracetamol or other traditional remedies, without seeking for consultation from general practitioners. Parents usually take the responsibility to come up with some kind of treatment for their children.

Aim: To explore the socio-demographic profile of the parents and to determine the effectiveness of awareness programme on knowledge of ill effect of self-medication among mothers of under-five children.

Material and methods: The evaluative, quasi experimental research design was adopted

60 Subjects (30 subjects in experimental group and 30 subjects in control group) were recruited by non- probability convenience sampling technique among mothers of under five children. The data gathering was carried out with a structured knowledge questionnaire. The collected data was optimized and analysed by using descriptive statistics and inferential statistics.

Aim and objectives: Diabetes mellitus (DM) is a metabolic and chronic disease with increasing prevalence worldwide. Inhibition of Dipeptidyl Peptidase - 4 prevents the inactivation of gastric inhibitory polypeptide (GIP) and increases Glucogan peptide like 1, an intestinal hormone that aids in glucose homeostasis and insulin secretion. In this study, potential and safer natural compounds were screened and validated biochemically for the identification of DPP- IV inhibitors. Methodology: The three dimensional structure of 1529 phytochemical compounds were retrieved from the following databases Pubchem, MAPS and NPACT. The compounds were subjected to drug likeliness screening using Chemo informatics software Molinspiration based on the Lipinski rule of five and also performed the bioavailability screening. Virtual screening followed by Molecular Docking was performed against the protein target dipeptidyl peptidase IV using iGEMDOCKV2.1 and Molecular Docking server .The identified lead compounds were tested for in vitro anti diabetic assays using α-amylase and α-glucosidase inhibition assay and compared with standard drug acarbose.  Results: Out of the 1529 compounds screened, 333 compounds satisfied the Lipinski rule of five. Philadelphicalactone A exhibited free energy binding of -4.37 Kcal/mol and Erysenegalensein E with a free energy binding of -3.65 Kcal/mol and showed interaction with the aminoacids at Gln72, Glu73, Asn75, Leu77, Asn87, Ser86 and Val88. Further, Philadelphicalactone A showed 48.6 % and 40.33 % of inhibition whereas Erysenegalensein E showed 55.39 % and 55.67 % inhibitory activity to α-amylase and α-glucosidase respectively.

Background: Zika virus is an arbovirus belongs to the genus flavivirus and pose a serious global threat. The recent 2015 outbreak in brazil was associated with a significant increase in microcepahly cases & other  neurological complications in new born babies and WHO declared ZIKA to be an international public health emergency. Currently there is no specific treatment or Vaccine available for the Zika virus and thus due to the unavailability of the antiviral drugs, the need for the identification of novel drugs are paramount.

Methodology: The compounds from two medicinal plants (Bacopa Monnieri and Euphorbia Hirta) were selected for the in silico molecular docking studies against the structural and nonstructural proteins of Zika virus.

Results:  Among the tested Compounds, galloylquinic acid, Bacopaside III and Bacopaside A were identified as leads against multiple targets of ZIKA virus. The identified compounds also exhibited desirable quantum chemical and ADMET Properties.

Conclusion: Hence the compounds hampering the active site of the three different proteins playing prime role in replication and fusion with desirable pharmacokinetics properties could be suggested for further in vitro and in vivo analysis of ZIKA virus.

Quarries which are located close to surface water or ground water often face problems leading to drainage. Pseudomonas aeruginosa, can be used for biodegradation in liquid culture, but the roles and production in soils are unknown. Surface-active compounds for bacterial production like biosurfactants and bioemulsifiers which will increase the hydrocarbons of local pseudosolubility and that will improve in mass transfer to biodegrading bacteria. Potassium solubilizing bacteria, such as Acidothiobacillus ferroxidans, Bacillus mucilogenous, Pseudomonas, Burkholderia, B. edaphicus and B. circulans can be used as biofertilizer. Hence this study is focused on isolation and identification of Pseudomonas aeroginosa from quarry sand and it will be used further for more application purposes.

Living systems encounter a variety of stresses during their continuous interaction with environment. Fish are particularly threatened by water pollution. In the present study the effect of nuclear pollution on fishes was investigated. Two ponds namely, one in Madras Christian College, Tambaram, and the other one in Kalpakkam were selected. The water samples collected from various points in the Kalpakkam pond were analyzed for twelve parameters like pH, hardness, iron content, chlorine content etc.

The sources of many of the new drugs and active ingredients of medicines are derived from natural products. The starting point for plant-based new drug discovery should be identification of the right candidate plants by applying traditional system of medicine. In many cases, the people claim the good remedy of such kind of plant -based products or herbal products. Chromatographical methods of separations of   bioactive principles from the plants are the most commonly used technique for the identification, quantification and characterisation purpose. Herbal medicinal plants are getting the paramount importance in the field of therapeutics, as most of the pharmaceutical industries are depend in on plants or plant materials for the production of pharmaceutical compounds. Therefore, it is of interest to investigate the antioxidant activity by DPPH-radical scavenging method in vitro. The results of the present study indicate that the aqueous extract of C.cerasiformis possess the strong antioxidant activities.

Plant based medicines and Phytochemicals can be potent agents for lung cancer chemoprevention and treatment by regulating multi-molecular targets involved in angiogenesis, metastasis, and severe side effects; only provided quality control and reproducibility issues are solved. Compared with the conventional drugs used in cancer treatment, the toxicity of medicinal plants may seem trivial; however, it is a serious public health problem. Several medicinal plants are considered toxic and can cause serious damage to the health of patients. Hence it is of interest to investigate the in vitro antioxidant analysis 0f ethyl acetate extract of Anisomeles malabarica was analysed. Our results indicate that the antioxidant potential of Anisomeles malabarica.

Background: Plant derived secondary metabolites make up a significant segment of natural product based pharmaceuticals especially from the  herbal medicinal plants. Hence, it is of interest to investigate the quantification of Phytochemicals such as total content of alkaloids, flavanoids, tannins and phenolic compounds are of our interest. Methods: Quantitative  analysis of phytocontituents of chloroform extract of Amalabarica were used to find out the quantification of Phytochemicals. Results: The results of the present study envisages that the presence of alkaloids,flavanoids,tannins and poly phenol compounds. Conclusion: The chloroform extract of Anisomeles malabarica contains pharmacologically active  phytochemical constituents.